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Selected Publications
Unraveling the effect of intra- and intercellular processes on acetaminophen-induced liver injury
In high dosages, acetaminophen (APAP) can cause severe liver damage, but susceptibility to liver failure varies across individuals and …
M. M. Heldring
,
A. H. Shaw
,
J. B. Beltman
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Selected Publications
Guidance by followers ensures long-range coordination of cell migration through α-catenin mechanoperception
Morphogenesis, wound healing, and some cancer metastases depend upon the migration of cell collectives that need to be guided to their …
Arthur Boutillon
,
Sophie Escot
,
Amélie Elouin
,
Diego Jahn
,
Sebastián González-Tirado
,
Jörn Starruß
,
Lutz Brusch
,
Nicolas B. David
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Selected Publications
Reoccurring neural stem cell divisions in the adult zebrafish telencephalon are sufficient for the emergence of aggregated spatiotemporal patterns
Regulation of quiescence and cell cycle entry is pivotal for the maintenance of stem cell populations. Regulatory mechanisms, however, …
V. Lupperger
,
C. Marr
,
P. Chapouton
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Self-organized multicellular structures from simple cell signaling: a computational model
Recent synthetic biology experiments reveal that signaling modules designed to target cell-cell adhesion enable self-organization of …
N. Mulberry
,
L. Edelstein-Keshet
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Heterogeneous, delayed-onset killing by multiple-hitting T cells: Stochastic simulations to assess methods for analysis of imaging data
Although quantitative insights into the killing behaviour of Cytotoxic T Lymphocytes (CTLs) are necessary for the rational design of …
R. J. Beck
,
D. I. Bijker
,
J. B. Beltman
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