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Cellular Potts Model
Selected Publications
Unraveling the effect of intra- and intercellular processes on acetaminophen-induced liver injury
In high dosages, acetaminophen (APAP) can cause severe liver damage, but susceptibility to liver failure varies across individuals and …
M. M. Heldring
,
A. H. Shaw
,
J. B. Beltman
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DOI
Model
Selected Publications
Reoccurring neural stem cell divisions in the adult zebrafish telencephalon are sufficient for the emergence of aggregated spatiotemporal patterns
Regulation of quiescence and cell cycle entry is pivotal for the maintenance of stem cell populations. Regulatory mechanisms, however, …
V. Lupperger
,
C. Marr
,
P. Chapouton
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Model
Selected Publications
Self-organized multicellular structures from simple cell signaling: a computational model
Recent synthetic biology experiments reveal that signaling modules designed to target cell-cell adhesion enable self-organization of …
N. Mulberry
,
L. Edelstein-Keshet
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Model
Selected Publications
Heterogeneous, delayed-onset killing by multiple-hitting T cells: Stochastic simulations to assess methods for analysis of imaging data
Although quantitative insights into the killing behaviour of Cytotoxic T Lymphocytes (CTLs) are necessary for the rational design of …
R. J. Beck
,
D. I. Bijker
,
J. B. Beltman
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DOI
Model
Selected Publications
A dynamic cell recruitment process drives growth of the Drosophila wing by overscaling the vestigial expression pattern
Organs mainly attain their size by cell growth and proliferation, but sometimes also grow through recruitment of undifferentiated …
L. M. Muñoz-Nava
,
H. A. Alvarez
,
M. Flores-Flores
,
O. Chara
,
M. Nahmad
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