CPM

Use logical operators and, or and xor in Condition for ChangeCellType. Introduction This example model demonstrates the use of logical operators. Please also see the built-in docu at GUI/Documentation/MathematicalExpressions.

This model also requires the separate file Population_M.csv with the list of lattice nodes where cells shall be initialized. Introduction Initializing the spatial configuration of cells is a key step of every simulation and Morpheus offers all the flexibility for this:

Particles moving left and right (as well as up) to mimic actin filament barbed ends Introduction Particles are moving left and right (as well as up) to mimic actin filament barbed ends as motivated by the referenced paper.

Demonstration of dynamically regulated cell-cell adhesion as a function of changing cell properties Model Get this model via: Morpheus-Link or  Download: CircleDance.xml XML Preview <MorpheusModel version="4"> <Description> <Title>Example-CircleDance</Title> <Details>Demonstration of dynamically regulated cell-cell adhesion as a function of changing cell properties.

Diffusion model with cells endowed with chemotactic ability Introduction Previously developed diffusion models can be used to model chemotaxis by adding cells endowed with chemotactic ability. Here, chemotaxis of a group of cells towards a chemical diffusing into the domain with a high level at the right boundary is demonstrated, as well as in a second model, Keller-Segel cells being the sources of their own attractant.

A simplified version of the Morpheus cell sorting example Introduction A simplified version of the Morpheus built-in example of M0021"cell sorting showing the effect of cell-cell and cell-medium contact energies on the tissue configuration.

An agent-based model where each cell’s position and velocity is tracked Introduction We expand our exploration of local and non-local models to the class of agent-based models. Description Instead of tracking continuous distributions of cell density, neural activity, or other properties that vary continuously across space, we adopt a different kind of modeling approach by tracking the trajectories and behavior of individual cells.

A diffusible small-RNA-based Turing system dynamically coordinates organ polarity. Introduction The formation of a flat and thin leaf presents a developmentally challenging problem, requiring intricate regulation of top-bottom (adaxial-abaxial) polarity.

Just over 30 years ago, the cellular Potts model (CPM) was introduced to explain experimental observations of spontaneous cell sorting …

Membrane pattern allows anisotropic release of substance into a chemical synapse Introduction Special cell types, like neurons or immune cells, communicate through a chemical synapse. This includes the anisotropic secretion of a substance into the gap between two cells.