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CPM
Selected Publications
Collective cell migration due to guidance-by-followers is robust to multiple stimuli
Collective cell migration is an important process during biological development and tissue repair but may turn malignant during tumor …
R. Müller
,
A. Boutillon
,
D. Jahn
,
J. Starruß
,
N. B. David
,
L. Brusch
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Model
Selected Publications
Unraveling the effect of intra- and intercellular processes on acetaminophen-induced liver injury
In high dosages, acetaminophen (APAP) can cause severe liver damage, but susceptibility to liver failure varies across individuals and …
M. M. Heldring
,
A. H. Shaw
,
J. B. Beltman
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DOI
Model
Selected Publications
Guidance by followers ensures long-range coordination of cell migration through α-catenin mechanoperception
Morphogenesis, wound healing, and some cancer metastases depend upon the migration of cell collectives that need to be guided to their …
Arthur Boutillon
,
Sophie Escot
,
Amélie Elouin
,
Diego Jahn
,
Sebastián González-Tirado
,
Jörn Starruß
,
Lutz Brusch
,
Nicolas B. David
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Model
Selected Publications
Reoccurring neural stem cell divisions in the adult zebrafish telencephalon are sufficient for the emergence of aggregated spatiotemporal patterns
Regulation of quiescence and cell cycle entry is pivotal for the maintenance of stem cell populations. Regulatory mechanisms, however, …
V. Lupperger
,
C. Marr
,
P. Chapouton
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Model
Selected Publications
Self-organized multicellular structures from simple cell signaling: a computational model
Recent synthetic biology experiments reveal that signaling modules designed to target cell-cell adhesion enable self-organization of …
N. Mulberry
,
L. Edelstein-Keshet
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Selected Publications
Heterogeneous, delayed-onset killing by multiple-hitting T cells: Stochastic simulations to assess methods for analysis of imaging data
Although quantitative insights into the killing behaviour of Cytotoxic T Lymphocytes (CTLs) are necessary for the rational design of …
R. J. Beck
,
D. I. Bijker
,
J. B. Beltman
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Model
Selected Publications
A dynamic cell recruitment process drives growth of the Drosophila wing by overscaling the vestigial expression pattern
Organs mainly attain their size by cell growth and proliferation, but sometimes also grow through recruitment of undifferentiated …
L. M. Muñoz-Nava
,
H. A. Alvarez
,
M. Flores-Flores
,
O. Chara
,
M. Nahmad
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